diff --git a/src/xenia/kernel/xboxkrnl/xboxkrnl_memory.cc b/src/xenia/kernel/xboxkrnl/xboxkrnl_memory.cc
index e8c2e2e84..ecb1d1c7c 100644
--- a/src/xenia/kernel/xboxkrnl/xboxkrnl_memory.cc
+++ b/src/xenia/kernel/xboxkrnl/xboxkrnl_memory.cc
@@ -425,8 +425,14 @@ DECLARE_XBOXKRNL_EXPORT2(MmQueryAddressProtect, kMemory, kImplemented,
 
 void MmSetAddressProtect_entry(lpvoid_t base_address, dword_t region_size,
                                dword_t protect_bits) {
-  if (!protect_bits) {
-    XELOGE("MmSetAddressProtect: Failed due to incorrect protect_bits");
+  constexpr uint32_t required_protect_bits =
+      X_PAGE_NOACCESS | X_PAGE_READONLY | X_PAGE_READWRITE |
+      X_PAGE_EXECUTE_READ | X_PAGE_EXECUTE_READWRITE;
+
+  if (xe::bit_count(protect_bits & required_protect_bits) != 1) {
+    // Many titles use invalid combination with zero valid bits set.
+    // We're skipping assertion for these cases to prevent unnecessary spam.
+    assert_false(xe::bit_count(protect_bits & required_protect_bits) > 1);
     return;
   }