diff --git a/3rdparty/CMakeLists.txt b/3rdparty/CMakeLists.txt
index 26b87b84c..2f224bc9d 100644
--- a/3rdparty/CMakeLists.txt
+++ b/3rdparty/CMakeLists.txt
@@ -378,7 +378,12 @@ endif()
 add_subdirectory(miniupnp EXCLUDE_FROM_ALL)
 
 # RTMIDI
-add_subdirectory(rtmidi EXCLUDE_FROM_ALL)
+if(NOT ANDROID)
+	add_subdirectory(rtmidi EXCLUDE_FROM_ALL)
+else()
+	add_library(rtmidi INTERFACE)
+	target_compile_definitions(rtmidi INTERFACE WITHOUT_RTMIDI)
+endif()
 
 # OPENCV
 add_subdirectory(opencv EXCLUDE_FROM_ALL)
diff --git a/rpcs3/Emu/Cell/lv2/sys_usbd.cpp b/rpcs3/Emu/Cell/lv2/sys_usbd.cpp
index cb0f15afa..e7dc92beb 100644
--- a/rpcs3/Emu/Cell/lv2/sys_usbd.cpp
+++ b/rpcs3/Emu/Cell/lv2/sys_usbd.cpp
@@ -537,6 +537,7 @@ usb_handler_thread::usb_handler_thread()
 			usb_devices.push_back(std::make_shared<usb_device_vfs>(usb_info, get_new_location()));
 	}
 
+#ifndef WITHOUT_RTMIDI
 	const std::vector<std::string> devices_list = fmt::split(g_cfg.io.midi_devices.to_string(), {"@@@"});
 	for (usz index = 0; index < std::min(max_midi_devices, devices_list.size()); index++)
 	{
@@ -569,6 +570,7 @@ usb_handler_thread::usb_handler_thread()
 			break;
 		}
 	}
+#endif
 }
 
 usb_handler_thread::~usb_handler_thread()
diff --git a/rpcs3/Emu/Io/RB3MidiDrums.cpp b/rpcs3/Emu/Io/RB3MidiDrums.cpp
index 999182ae0..d21efe528 100644
--- a/rpcs3/Emu/Io/RB3MidiDrums.cpp
+++ b/rpcs3/Emu/Io/RB3MidiDrums.cpp
@@ -1,6 +1,8 @@
 // Rock Band 3 MIDI Pro Adapter Emulator (drums Mode)
 
 #include "stdafx.h"
+
+#ifndef WITHOUT_RTMIDI
 #include "RB3MidiDrums.h"
 #include "Emu/Cell/lv2/sys_usbd.h"
 #include "Emu/Io/rb3drums_config.h"
@@ -838,3 +840,5 @@ std::optional<rb3drums::KitState> usb_device_rb3_midi_drums::ComboTracker::take_
 	}
 	return {};
 }
+
+#endif
diff --git a/rpcs3/Emu/Io/RB3MidiDrums.h b/rpcs3/Emu/Io/RB3MidiDrums.h
index 60a2874ce..147a9a768 100644
--- a/rpcs3/Emu/Io/RB3MidiDrums.h
+++ b/rpcs3/Emu/Io/RB3MidiDrums.h
@@ -1,5 +1,7 @@
 #pragma once
 
+#ifndef WITHOUT_RTMIDI
+
 #include "Emu/Io/usb_device.h"
 
 #include <rtmidi_c.h>
@@ -155,3 +157,5 @@ private:
 	bool is_midi_cc(u8 id, u8 value);
 	void write_state(u8* buf, const rb3drums::KitState&);
 };
+
+#endif
diff --git a/rpcs3/Emu/Io/RB3MidiGuitar.cpp b/rpcs3/Emu/Io/RB3MidiGuitar.cpp
index 54654c24c..c98701c75 100644
--- a/rpcs3/Emu/Io/RB3MidiGuitar.cpp
+++ b/rpcs3/Emu/Io/RB3MidiGuitar.cpp
@@ -1,6 +1,9 @@
 // Rock Band 3 MIDI Pro Adapter Emulator (Guitar Mode)
 
 #include "stdafx.h"
+
+#ifndef WITHOUT_RTMIDI
+
 #include "RB3MidiGuitar.h"
 #include "Emu/Cell/lv2/sys_usbd.h"
 
@@ -370,3 +373,5 @@ void usb_device_rb3_midi_guitar::write_state(u8* buf)
 
 	buf[2] = button_state.dpad;
 }
+
+#endif
diff --git a/rpcs3/Emu/Io/RB3MidiGuitar.h b/rpcs3/Emu/Io/RB3MidiGuitar.h
index 3a93f95d6..85474a023 100644
--- a/rpcs3/Emu/Io/RB3MidiGuitar.h
+++ b/rpcs3/Emu/Io/RB3MidiGuitar.h
@@ -1,5 +1,7 @@
 #pragma once
 
+#ifndef WITHOUT_RTMIDI
+
 #include "Emu/Io/usb_device.h"
 
 #include <rtmidi_c.h>
@@ -42,3 +44,5 @@ public:
 	void control_transfer(u8 bmRequestType, u8 bRequest, u16 wValue, u16 wIndex, u16 wLength, u32 buf_size, u8* buf, UsbTransfer* transfer) override;
 	void interrupt_transfer(u32 buf_size, u8* buf, u32 endpoint, UsbTransfer* transfer) override;
 };
+
+#endif
diff --git a/rpcs3/Emu/Io/RB3MidiKeyboard.cpp b/rpcs3/Emu/Io/RB3MidiKeyboard.cpp
index ccfc2dbdc..0a1bfcf6b 100644
--- a/rpcs3/Emu/Io/RB3MidiKeyboard.cpp
+++ b/rpcs3/Emu/Io/RB3MidiKeyboard.cpp
@@ -1,6 +1,7 @@
 // Rock Band 3 MIDI Pro Adapter Emulator (Keyboard Mode)
-
 #include "stdafx.h"
+
+#ifndef WITHOUT_RTMIDI
 #include "RB3MidiKeyboard.h"
 #include "Emu/Cell/lv2/sys_usbd.h"
 
@@ -355,3 +356,5 @@ void usb_device_rb3_midi_keyboard::write_state(u8* buf)
 		buf[15] = std::min<u8>(std::max<u8>(0x5, wheel_pos), 0x75);
 	}
 }
+
+#endif
diff --git a/rpcs3/Emu/Io/RB3MidiKeyboard.h b/rpcs3/Emu/Io/RB3MidiKeyboard.h
index c5042af23..e642831e3 100644
--- a/rpcs3/Emu/Io/RB3MidiKeyboard.h
+++ b/rpcs3/Emu/Io/RB3MidiKeyboard.h
@@ -1,5 +1,7 @@
 #pragma once
 
+#ifndef WITHOUT_RTMIDI
+
 #include "Emu/Io/usb_device.h"
 
 #include <rtmidi_c.h>
@@ -47,3 +49,4 @@ public:
 	void control_transfer(u8 bmRequestType, u8 bRequest, u16 wValue, u16 wIndex, u16 wLength, u32 buf_size, u8* buf, UsbTransfer* transfer) override;
 	void interrupt_transfer(u32 buf_size, u8* buf, u32 endpoint, UsbTransfer* transfer) override;
 };
+#endif